HLA-E monoclonal antibody, clone MEM-E/07 (Biotin)
产品名称: HLA-E monoclonal antibody, clone MEM-E/07 (Biotin)
英文名称: HLA-E monoclonal antibody, clone MEM-E/07 (Biotin)
产品编号: MAB9791
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
                            亚诺法生技股份有限公司(Abnova)
                            
                                
                            
                        
                    - 联系人 :
 - 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
 - 邮编 : 11493
 - 所在区域 : 台湾
 - 电话 : +886-920**1152 点击查看
 - 传真 : 点击查看
 - 邮箱 : sales@abnova.com.tw
 
- Specification
 
- Product Description:
 - Mouse monoclonal antibody raised against recombinant HLA-E.
 
- Immunogen:
 - Recombinant protein corresponding to human HLA-E.
 
- Host:
 - Mouse
 
- Reactivity:
 - Human
 
- Specificity:
 - The antibody MEM-E/07 recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells.
 
- Form:
 - Liquid
 
- Conjugation:
 - Biotin
 
- Concentration:
 - 1 mg/mL
 
- Isotype:
 - IgG1
 
- Storage Buffer:
 - In PBS, pH 7.4 (15 mM sodium azide)
 
- Storage Instruction:
 - Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. 
- Recommend Usage:
 - Flow Cytometry (2 ug/mL)
The optimal working dilution should be determined by the end user. 
- Note:
 - This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
 
- Application Image
 
- Flow Cytometry
 
- Entrez GeneID:
 - 3133
 
- Gene Name:
 - HLA-E
 
- Gene Alias:
 - DKFZp686P19218,EA1.2,EA2.1,HLA-6.2,MHC,QA1
 
- Gene Description:
 - major histocompatibility complex, class I, E
 
- Omim ID:
 - 143010
 
- Gene Ontology:
 - Hyperlink
 
- Gene Summary:
 - HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq
 
- Other Designations:
 - HLA class I histocompatibility antigen, E alpha chain,MHC HLA-E alpha-1,MHC HLA-E alpha-2.1,MHC class I antigen,OTTHUMP00000029214,lymphocyte antigen
 
- Related Disease
 
- Abortion, Habitual
 - Abortion, Spontaneous
 - Acute Disease
 - Anemia, Sickle Cell
 - Anemia, sickle cell
 - Bacterial Infections
 - Behcet Syndrome
 - Bone Marrow Diseases
 - Carcinoma
 - Chorioamnionitis
 - Coronary Aneurysm
 - Cytomegalovirus Infections
 - Fetal Membranes, Premature Rupture
 - Genetic Predisposition to Disease
 - Graft vs Host Disease
 - HIV Infections
 - Lupus Erythematosus, Systemic
 - Mucocutaneous Lymph Node Syndrome
 - Nasopharyngeal Neoplasms
 
